Indium catalyzed tandem hydroamination/hydroalkylation of terminal alkynes.

نویسندگان

  • Rupam Sarma
  • Dipak Prajapati
چکیده

The first direct intermolecular hydroamination/hydroalkylation of terminal alkynes catalyzed by In(OTf)(3) under one-pot conditions leading to the formation of conjugated ketimines in good yields is described.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Rsc_cc_c1cc13486h 1..3

In recent years, considerable effort has been devoted to develop methodologies which reduce multi-step transformations into one-step tandem processes. In this regard, the use of multifunctional catalysts, which promote sequential reaction steps without additional requirement of additives and/or co-catalysts, provides an effective way while taking care of two most basic challenges faced by a syn...

متن کامل

Sequential Copper(I)-Catalyzed Reaction of Amines with o-Acetylenyl-Substituted Phenyldiazoacetates

A highly efficient, tetrakis(acetonitrile)copper(I) hexafluorophosphate [Cu ACHTUNGTRENNUNG(MeCN)4PF6]catalyzed tandem Cu(I)-carbene N H insertion/ Cu(I)-catalyzed hydroamination of alkynes, which leads to sequential formation of two C N bonds to yield isoindole derivatives, has been developed.

متن کامل

Hydroamination of terminal alkynes with secondary amines catalyzed by copper: regioselective access to amines.

A simple and convenient copper-catalyzed hydroamination of arylacetylenes with secondary amines has been performed giving a simple access to aliphatic amines after reduction of the hydroaminated products (E-enamines). Here we described a mild catalytic system utilizing CuCN precatalyst without any additive ligands in a solvent-free system.

متن کامل

Hydroamination of Terminal Alkynes by Amines Catalyzed by Copper Heteropoly Salts: A Simple Approach Towards Imine Synthesis

The hydroamination reaction offers a very attractive route for the synthesis of alkylated amines and their derivatives with no byproduct formation. Heterogeneous intermolecular hydroamination reactions of alkynes with aromatic amines using different inexpensive copper salts of hetropolyacid catalysts were investigated. Among heteropoly salts, copper salts of silicotungstic acid showed highest a...

متن کامل

N-Sulfonylketenimines as Useful Synthons in a Novel Synthesis of Functionalized 2-Oxoindoline Derivatives

The synthesis of a novel class of 2-oxoindolin-3-ylidene-(1-arylhydrazinyl)-2-aryl(alkyl)ethylidene derivativesvia a copper-catalyzed tandem reaction of isatin, arylhydrazines, sulfonyl azides and terminal alkynes is described.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 47 33  شماره 

صفحات  -

تاریخ انتشار 2011